Correlation Between Postoperative Antimicrobial Prophylaxis Use and Surgical Site Infection in Children Undergoing Nonemergent Surgery

 In this multicenter hospital-level cohort study of children undergoing nonemergent surgery, use of postoperative prophylaxis was not correlated with surgical site infection rates after adjusting for differences in procedure mix and patient characteristics among hospitals.

These findings further support the recommendations of national and international organizations to discontinue postoperative prophylaxis after skin closure.